Do we need to measure specific antibodies in patients with limbic encephalitis?
نویسندگان
چکیده
منابع مشابه
O 15: Limbic Encephalitis: General Aspects of Pathophysiology, Symptoms and Therapeutic Options
Patients with limbic encephalitis usually present with new onset mesial temporal lobe seizures, progressive memory disturbance, and a variety of other behavioral, emotional, and cognitive changes. Autoimmune inflammation of the limbic gray matter structures of the human brain has recently been identified as major cause of mesial temporal lobe epilepsy with interictal temporal epileptiform activ...
متن کاملInvestigation of LGI1 as the antigen in limbic encephalitis previously attributed to potassium channels: a case series.
BACKGROUND Voltage-gated potassium channels are thought to be the target of antibodies associated with limbic encephalitis. However, antibody testing using cells expressing voltage-gated potassium channels is negative; hence, we aimed to identify the real autoantigen associated with limbic encephalitis. METHODS We analysed sera and CSF of 57 patients with limbic encephalitis and antibodies at...
متن کاملVoltage-gated potassium channel-complex antibody-associated limbic encephalitis.
OBJECTIVE Autoantibodies against glutamic acid decarboxylase (GAD) and the voltage-gated potassium channel (VGKC) complex are associated with distinct subtypes of limbic encephalitis regarding clinical presentation, response to therapy, and outcome. The aim of this study was to investigate white matter changes in these two limbic encephalitis subtypes by means of diffusion tensor imaging (DTI)....
متن کاملO 17: Childhood Anti-NMDA Receptor Encephalitis
Anti N-methyl-D-aspartate receptor (NMDR) encephalitis has been recognized as the most frequent autoimmune encephalitis in children after acute demyelinating encephalomyelitis (ADEM).However due to the variable the variable clinical presentation, the paucity of specific finding on standard laboratory and radiological investigation remains under recognized. First discribed in 2005, most commonly...
متن کاملOpsoclonus-myoclonus and anti-Hu positive limbic encephalitis in a patient with neuroblastoma.
Opsoclonus-myoclonus syndrome (OMS) is seen in 2-3% of children with neuroblastoma and is believed to be caused by an autoimmune process elicited by the tumor. Although long-term neurologic sequelae are common in children with OMS, limbic encephalitis has not previously been reported. We report a child who developed limbic encephalitis associated with anti-Hu antibodies, 6 years after her initi...
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ورودعنوان ژورنال:
- Neurology
دوره 88 6 شماره
صفحات -
تاریخ انتشار 2017